Post-vagotomy diarrhoea.
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Post-vagotomy diarrhoea. by Geoffrey Blake

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Published .
Written in English

Book details:

Edition Notes

Thesis (M.D.)--The Queen"s University of Belfast,1981.

The Physical Object
Pagination1 v
ID Numbers
Open LibraryOL19320249M

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  REFERENCES 1. J.G. Allan, V.P. Gerskowitch, R.I. Russell, A study of the role of bile acids in the pathogenesis of Post-vagotomy diarrhea Gut () J.G. Allan, R.I. Russell, Double-blind controlled trial of cholestyramine in the treatment of Post-vagotomy diarrhea . Most patients have an alteration in bowel habits after gastric surgery, particularly if gastric surgery is accompanied by vagotomy. It is probably because of the close association of diarrhoea with sectioning of the vagus nerves observed by Dragstedt et al. [1] that he term postvagotomy diarrhoea .   Thank you for your interest in spreading the word about The BMJ. NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk by: 9. The diarrhoea responded completely to therapy, during which the stool content of water, sodium, postassium and magnesium fell. Two of the patients, while receiving cholestyramine, had a rise in faecal fat, but this was not accompanied by diarrhoea, the stools being well formed. Evidence is presented which suggests that the mechanism of.

Fig. 4-Incidence of post- vagotomy diarrhoea. Pale Stools Fig. 6 shows that the proportion of patients having pale stools after operation was also much lower with the ty-pe-3 operation. While colour change was not necessarily associated with diarrhoea, 70% of patients having diarrhoea also had pale stools.   Journal of Psychosomatic Research, pp to Pergamon Press, , Printed in Great Britain PSYCHIATRIC DISTURBANCE AND POST VAGOTOMY DIARRHOEA* EVE C JOHNSTONE,j.T G ALLAN,T B P GERAGHTY and R I RUSSELLt (Received 7 February ) THIS STUDY was conducted with a view to examining the possibility that patients who developed diarrhoea . Post-vagotomy diarrhea is a form of diarrhea which occurs in 10% of people after a truncal vagotomy, which can range from severe to debilitating in approximately 2% to 4% of patients. However, the occurrence of post-vagotomy diarrhea is significantly reduced after proximal selective vagotomy, specifically when celiac and hepatic branches of the vagus are retained. In the past, vagotomy and Billroth I or II gastric resections were used frequently for peptic ulcer disease or gastric cancer and were associated with some element of post gastrectomy/vagotomy syndrome in 25% of patients. These symptoms (diarrhea, early satiety, gastric stasis) were mild, self-limited, and only rarely needed operative treatment.

Post-vagotomy diarrhoea probably results froma combina-tion of unregulated gastric emptying and denervation of the small bowel. It occurs in about 25% of patients after truncal vagotomy. Forthe majority the increased frequency of bowel action is an unexpected bonus of the operation. The in-cidence of severe and disabling diarrhoea is low. Cholecystectomy increases the risk of post‐vagotomy diarrhoea and bile acid binding agents may relieve it, suggesting a role for bile acids in its pathogenesis. The faecal bile acid loss in 15 patients with episodic diarrhoea after vagotomy and drainage was not raised when compared with 12 normal subjects, except on days when diarrhoea occurred. In the early postoperative period after the combined procedure there was a very high incidence of post-vagotomy diarrhoea (%, P equal to ) and bile-reflux gastritis.   Introduction - THE cause of post-vagotomy diarrhoea remains un- known. An association between cholecystectomy and the incidence of post-vagotomy diarrhoea' supports the theory that the excretion of bile acids, their chemical composition, and their handling by the small bowel may be important in the pathogenesis of post-vagotomy diarrhoea.